Drug Name | GPCR-targeted Project 007 |
Description |
A bispecific antibody that simultaneously targets two cancer stem cell receptors (LGR5 and LGR4) is in early preclinical development for the treatment of solid tumors. |
Target | Leucine-rich repeat-containing G protein-coupled receptor 4 (LGR4); Leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5) |
Drug Modality | Bispecific antibody |
Indication | Solid tumors |
Product Category | Biologic |
Mechanism of Action | G protein-coupled receptor antagonists |
Status | Preclinical |
Patent | Granted |
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