Drug Name | GPCR-targeted Project 005 |
Description |
Prokineticins (PK1 and PK2) are peptide hormones that exert their biological activities, such as modulating cell survival, cell motility, and cell excitability, through two common G-protein-coupled receptors: prokineticin receptor (PKR) 1 and 2. A monoclonal antibody is being developing as an inhibitor of prokineticin receptor 1 (PKR1) for the treatment of inflammation. Early research is under way. |
Target | Prokineticin receptor 1 (PKR1) |
Drug Modality | Monoclonal antibody |
Indication | Inflammation |
Product Category | Biologic |
Mechanism of Action | PKR1 inhibitors |
Status | Preclinical |
Patent | Granted |
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