|Drug Name||GPCR-targeted Project 016|
Frizzled 7 (FZD7) is a critical receptor for Wnt signaling, which binds to Wnt proteins to activate either canonical or noncanonical Wnt signaling pathways. The Wnt/β-catenin signaling pathway is involved in the regulation of cell proliferation, differentiation, migration, apoptosis, and survival, and has been shown to be dysregulated in cancers.
|Target||Frizzled 7 (FZD7)|
|Drug Modality||Monoclonal antibody|
|Mechanism of Action||Frizzled 7 antagonists|
We look forward to hearing from you.